Pathogenesis of Picornavirus

Senecavirus A is a re-emergiging disease of swine. It causes vesicular disease in swine. Despite detection of Senecavirus A nucleic acid in pigs with vesicular disease, attemps to establish causal relationship had failed. We were able to reproduce the disease in swine and we have published a detail pathogenesis of Senecavirus A in this paper. We have also showed that the virus establishes persistent infection in infected animal.

Lok Raj Joshi
Lok Raj Joshi
Postdoctoral Research Fellow

My research interests include AAV gene therapy, vectored vaccine development, viral pathogenesis, diagnostic assay development,reverse genetics, viral bioinformatics.