Pathogenesis of Picornavirus
Senecavirus A is a re-emergiging disease of swine. It causes vesicular disease in swine. Despite detection of Senecavirus A nucleic acid in pigs with vesicular disease, attemps to establish causal relationship had failed. We were able to reproduce the disease in swine and we have published a detail pathogenesis of Senecavirus A in this paper. We have also showed that the virus establishes persistent infection in infected animal.